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ESM

Product2 stories

  1. ResearchReach 36

    Biohub's AI designs lab-proven antibodies in days

    Biohub just unveiled ESM, a protein "world model" featuring the ESMFold2 design engine, a 2.8B-sequence model called ESMC, and an atlas of 1.1 billion predicted structures. Instead of spending months physically screening candidate binders in a lab, researchers can now design and rank functional antibodies computationally in just a few days. Lab tests against five cancer and immune targets, confirmed via cryo-EM, prove the designs actually work.

  2. ResearchReach 48

    ProtGPS maps where proteins belong inside cells

    MIT and Whitehead Institute researchers just introduced ProtGPS, a deep-learning model that predicts how proteins sort themselves within cellular condensates. Built on Meta's ESM framework, it complements AlphaFold's structural predictions by decoding spatial organization rules, paving the way for targeted drug discovery.