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DeepMind opens AlphaFold 3 code to researchers

Published Reach 38

Google DeepMind just released the software code for its protein-folding model AlphaFold 3 for non-commercial scientific research. The release follows six months of academic backlash over withholding the code, though accessing the actual model weights still requires an application request.

DeepMind opens AlphaFold 3 code to researchers
Image: nature.com

AlphaFold 3 is Google DeepMind's flagship protein-structure prediction tool. On November 11, DeepMind made the software code available for researchers to download and run for non-commercial scientific applications.

Code is available, but weights still require approval

Six months ago, DeepMind sparked serious backlash across the scientific community after publishing a Nature paper without releasing the underlying code. This update addresses some of those complaints, but it is not a traditional open-source release.

While scientists can now download the software code, it is restricted to non-commercial use. More importantly, the model weights are not included in the public repository; researchers still have to submit an access request to DeepMind to get them.

Why it matters

For academic biologists and non-commercial labs, this makes AlphaFold 3 much more useful by letting researchers inspect the architecture and run non-commercial pipelines locally.

However, biotech startups and commercial pharma remain entirely locked out. In our view, DeepMind found a middle ground to calm academic outrage while protecting its proprietary edge, but keeping the weights behind an application form means the model is still far from truly open.

Sources (1)

  1. [1]
    nature.com(opens in a new tab)Originalnature.com

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